Alexander Green FRCS(SN), MD, BSc

Oxford Functional Neurosurgery and Experimental Neurology (OFNEN)
Central Nervous System control of the Autonomic Nervous System, Pain and Deep Brain Stimulation.
Email
Tel 01865 234762
Fax 01865 231885
PA Jo Lavender
Email (PA)
Fax (PA) 01865 234605
Contact address Department of Neurosurgery, West Wing Level 3, John Radcliffe Hospital, Oxford OX3 9DU

Research summary

Over the past 6 years I have been looking at the neurocircuitry underlying autonomic function and pain in humans undergoing Deep Brain Stimulation (DBS). There are several aims of this research. Firstly, I wish to understand both the mechanisms underlying the pathophysiology of neuropathic pain as well as why some patients get much better than results than others. Secondly, by understanding the autonomic nervous system, it may be possible to control diseases such as hypertension, respiratory and bladder disease by brain manipulation in the future. Most of the research to date has involved stimulating brain areas under different experimental conditions and also recording local field potentials to understand the underlying neurophysiology. This work has resulted in a number of publications including improvement in peak expiratory flow with stimulation, the effect of stimulation on blood pressure and baroreceptors sensitivity and novel electrical signals associated with pain states

Sources of Funding

Biography

I studied medicine at University College London qualifying MB BS in 1997. I obtained a first class honours in Neurosciences (intercalated) in 1994. After house jobs and a basic surgical rotation in the West Midlands, I entered Neurusurgical training in London then Oxford from 2002-2009. I completed a MD degree in Oxford in the role of the periaqueductal grey area in autonomic control during this time. I became a consultant neurosurgeon in 2009. I am currently president of the British Society for Stereotactic and Functional Neurosurgery (BSSFN).

Awards Training and Qualifications

  • FRCS (SN)  Royal College of Surgeons of England 2007
  • Doctor of Medicine  University of London 2005- 2007
  • MB BS  University College London 1991- 1997
  • BSc (Hons)  University College London 1994
  • New Investigator Award  International Neuromodulation Society 2010
  • 7th Cluster Headache Award  International Annual Convention on Cluster Headache 2010
  • Stereotactic and Functional Neurosurgery Resident Award  Congress of Neurological Surgeons (USA) 2005
  • Gordon Holmes Prize  Royal Society of Medicine 2005

Collaborators

  • Prof Peter Brown
  • Prof Tipu Aziz
  • Prof David Paterson, Professor of Physiology , DPAG
  • Dr Thelma Lovick, reader in Physiology , University of Birmingham
  • Prof Morten Kringelbach, neuroscientist , Dept of Psychiatry, University of Oxford